Mechanisms of KCNQ1 gating modulation by KCNE1/3 for cell-specific function
Chenxi Cui, Lu Zhao, Ali A. Kermani…·Ji Sun
This study investigates how KCNE1 and KCNE3 modulate KCNQ1 gating through PIP2-dependent mechanisms, revealing distinct roles in voltage sensitivity and GPCR regulation across cell types.