Rafael Alcalá‐Vida

This study shows that KAT3 proteins are essential for maintaining neural cell identity, and their degradation or restoration affects transcriptome and physiological functions in neuronal and glial cells.

This study shows increased lamin B1 levels in HD neurons disrupt nuclear function, and reducing lamin B1 with betulinic acid improves nuclear homeostasis and prevents motor and cognitive dysfunction in a mouse model.