Author

Sasha Burwell

Duke UniversityORCID 0000-0003-3553-1365Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Brenda C. ShieldsiD· 3 shared Hai YaniD· 3 shared Michael R. TadrossiD· 3 shared Shaun S.X. LimiD· 3 shared Aaron T HalvorseniD· 1 shared Allen B. ReitziD· 1 shared Andrew I. AldridgeiD· 1 shared Anne E. WestiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Brenda C. ShieldsORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 27, 2026

Connectomic dopamine-neuron disinhibition accelerates behavioral extinction

Sasha Burwell, Rene Carter, Hai Yan…·Michael R. Tadross

The paper shows that weakening inhibitory synapses onto dopamine neurons accelerates behavioral extinction by reducing reward-omission dopamine dips.

DOI 10.64898/2026.08.24.746800

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 5, 2026

Transcriptional plasticity of ventral tegmental area neurons induced after cessation of chronic cocaine exposure is required for incubation of cocaine seeking

Arthy Narayanan, Kendyl N. Laumann, Aaron T Halvorsen…·Anne E. West

The paper investigates transcriptional changes in VTA neurons after chronic cocaine cessation and their role in relapse, finding that BDNF transcription is causally linked to cocaine seeking.

DOI 10.64898/2026.06.30.735717

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 9, 2024

Natural phasic inhibition of dopamine neurons signals cognitive rigidity

Sasha Burwell, Hai Yan, Shaun S.X. Lim…·Michael R. Tadross

The paper shows that blocking natural phasic inhibition of dopamine neurons accelerates extinction learning and benefits perseverative mice.

4 citations

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 18, 2022

Thousandfold Cell-Specific Pharmacology of Neurotransmission

Brenda C. Shields, Hai Yan, Shaun S.X. Lim…·Michael R. Tadross

The paper introduces DART.2, a method for cell-specific drug delivery, demonstrating robust bidirectional editing of neurotransmission in mice.

5 citations

mouseexperimental assay

𝕏 PostBluesky