Author
National Center for Advancing Translational SciencesORCID 0000-0003-3580-380XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Ying Fu, Juliana da Fonseca Rezende e Mello, Bryan D. Fleming…·Anton M. Simeonov
This paper develops potent humanized nanobodies against SARS-CoV-2 spike protein, showing effectiveness against the Alpha variant and providing structural insights into their neutralization mechanism.
Holli‐Joi Martin, Cleber Camilo Melo-Filho, Daniel Korn…·Alexander Tropsha
The paper curates a database of antiviral compounds tested against 13 emerging viruses, identifies potential broad-spectrum antivirals, and highlights the need for coordinated research efforts.
Joshua E. Hochuli, Sankalp Jain, Cleber Camilo Melo-Filho…·Alexey V. Zakharov
The paper identifies five compounds that inhibit SARS-CoV-2 replication by binding to ACE2 without disrupting its enzymatic function, serving as potential acute treatments for COVID-19.