Author

Ryan J. Kast

Broad InstituteORCID 0000-0003-3580-8811Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Guoping FengiD· 2 shared Alexandra L. LanjewariD· 1 shared Alexis ArnaudoniD· 1 shared Borislav DejanoviciD· 1 shared Colton D. Smith· 1 shared Dongqing WangiD· 1 shared Hasmik KeshishianiD· 1 shared Jonathan J. WildeiD· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersNeuroscience

Guoping FengORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 8, 2024

Biophysical modeling of thalamic reticular nucleus subpopulations and their differential contribution to network dynamics

Polina Litvak, Nolan D. Hartley, Ryan J. Kast…·Sean Hill

The paper develops biophysically detailed models of thalamic reticular neurons to study their firing properties and impact on network dynamics.

1 citation

mouseelectronic health records

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 15, 2024

Brain-region-specific changes and dysregulation of activity regulated genes in Gria3 mutant mice, a genetic animal model of schizophrenia

Wei-Chao Huang, Ryan J. Kast, Kira A. Perzel Mandell…·Morgan Sheng

This study examines Gria3 mutant mice to identify transcriptomic and proteomic changes linked to schizophrenia, finding region-specific gene dysregulation and synaptic protein alterations.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologyeLifePeer-reviewedMay 17, 2019

FOXP2 exhibits neuron class specific expression, but is not required for multiple aspects of cortical histogenesis

Ryan J. Kast, Alexandra L. Lanjewar, Colton D. Smith, Pat R. Levitt

The paper examines FOXP2 expression and function in mouse cortical development, finding that its removal does not disrupt many previously proposed developmental processes.

44 citations

mouseexperimental assay

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