Author

Jennifer L. Tenor

Duke UniversityORCID 0000-0002-1463-7243Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:fungi (other)· 3 Research Focus:drug response / drug discovery· 2 Research Focus:GWAS / association mapping· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

John R. PerfectiD· 3 shared Charles D. GiamberardinoiD· 2 shared Christina A. CuomoiD· 2 shared Adrienne Kit ChaniD· 1 shared Alexander M. Jones· 1 shared Alexander R. Jenner· 1 shared Anastasia P. LitvintsevaiD· 1 shared Cecilia KanyamaiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

John R. PerfectORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inhibitors of trehalose-6-phosphate synthase activity in fungal pathogens compromise thermal tolerance pathways

Yi Miao, Vikas Yadav, William R. Shadrick, Jiuyu Liu, Alexander R. Jenner, Connie B. Nichols, Clifford T. Gee, Martin Schäfer, Jennifer L. Tenor, John R. Perfect, Richard E. Lee Jr., Richard G. Brennan, E. Washington

This paper identifies 4456dh, a small molecule inhibitor of trehalose-6-phosphate synthase, which disrupts fungal thermal tolerance and virulence.

mBio · Aug 25, 2025Peer-reviewedMicrobiology

Genomic variation across a clinical Cryptococcus population linked to disease outcome

Poppy Sephton-Clark, Jennifer L. Tenor, Dena L. Toffaletti, Nancy Meyers, Charles D. Giamberardino, Síle F. Molloy, Julia R. Palmucci, Adrienne Kit Chan, Tarsizio Chikaonda, Robert S. Heyderman, Mina C. Hosseinipour, Newton L. Kalata, Cecilia Kanyama, Christopher Kukacha, Duncan Lupiya, , Christina A. Cuomo

This study links genetic variation in Cryptococcus neoformans to clinical outcomes and virulence in animal models using GWAS and genomic data from 284 isolates.

mBio · Nov 10, 2022Peer-reviewedGenomics

Population Genomics And The Evolution Of Virulence In The Fungal Pathogen Cryptococcus neoformans

Christopher A. Desjardins, Charles D. Giamberardino, Sean M. Sykes, Chen-Hsin Albert Yu, Jennifer L. Tenor, Yuan Chen, Timothy Yang, Alexander M. Jones, Sheng Sun, Miriam R. Haverkamp, Joseph Heitman, Anastasia P. Litvintseva, John R. Perfect, Christina A. Cuomo

This study uses population genomics to explore how environmental selective pressures shaped virulence traits in Cryptococcus neoformans, identifying genetic differences between clinical and environmental isolates.

Genome Research · Jul 1, 2017Peer-reviewedGenomics