Author

Dong Geun Lee

St. Jude Children's Research HospitalORCID 0000-0003-3668-0485Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Abhijit DasguptaiD· 1 shared Anand Mayasundari· 1 shared Andrew Tang· 1 shared Angelina Li· 1 shared Anup AggarwaliD· 1 shared Barbora Vagnerova· 1 shared Boer Xie· 1 shared Danting LiuiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Abhijit DasguptaORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 3, 2025

LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia

Jun J Yang, Gisele Nishiguchi, Satoshi Yoshimura…·Marcus M. Fischer

This study develops LCK-targeting molecular glues that overcome resistance to kinase inhibitors in T-ALL by inducing CRBN-dependent degradation of LCK.

1 citation

humanproteomics

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BiochemistryNature CommunicationsPeer-reviewedFeb 11, 2025

✦ In-depth digest

Human-mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome

Jay M. Yarbro, Xian Han, Abhijit Dasgupta…·Junmin Peng

Alzheimer's mouse model proteomes capture 30% (amyloid-only models) to 42% (adding tau and splicing models) of consensus human AD protein changes; in 5xFAD, plaques slow degradation of plaque-associated proteins.

41 citationstop 1%

mousehuman

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