Author

Boer Xie

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Junmin PengiD· 2 shared Yingxue FuiD· 2 shared Yuxin LiiD· 2 shared Abhijit DasguptaiD· 1 shared Aishwarya C. Ballapuram· 1 shared Andrew Tang· 1 shared Barbora Vagnerova· 1 shared Benjamin F. CravattiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Junmin PengORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Multi-Omics Study of Cognitive Resilience to Alzheimer's Disease

Erming Wang, Boer Xie, Minghui Wang, Yingxue Fu, Xusheng Wang, Yuxin Li, Peng Xu, Huaping Liu, Lap Ho, Zhidong Tu, Charles V. Mobbs, Chris Gaiteri, Michelle E. Ehrlich, David A. A Bennett, Vahram H. Haroutunian, , Bin Zhang

The paper develops a multi-omics cohort of prefrontal cortex data from cognitively normal older adults to identify molecular signatures of cognitive resilience to Alzheimer's disease.

bioRxiv · Sep 6, 2026 · PreprintGenomics

In vivo validation of the palmitoylation cycle as a therapeutic target in NRAS-mutant cancer

Matthew Decker, Benjamin J. Huang, Timothy B. Ware, Christopher D. Boone, Michelle Tang, Julia Ybarra, Matthew J. Sale, Rony A. Francois, Aishwarya C. Ballapuram, Katrine A. Taran, Esteban Tarazona-Guzman, Pan-Yu Chen, Marcos Armendariz, Camille J. Leung, Max Harris, , Kevin Shannon

This study validates the palmitoylation cycle as a therapeutic target in NRAS-mutant cancers by showing that inhibiting ABHD17 reduces tumor growth and synergizes with MEK inhibitors.

bioRxiv · Mar 20, 2025 · PreprintCancer Biology

Human-mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome

Jay M. Yarbro, Xian Han, Abhijit Dasgupta, Ka Yang, Danting Liu, Him K. Shrestha, Masihuz Zaman, Zhen Wang, Kaiwen Yu, Dong Geun Lee, David Vanderwall, Mingming Niu, Huan Sun, Boer Xie, Ping‐Chung Chen, , Junmin Peng

Alzheimer's mouse model proteomes capture 30% (amyloid-only models) to 42% (adding tau and splicing models) of consensus human AD protein changes; in 5xFAD, plaques slow degradation of plaque-associated proteins.

Nature Communications · Feb 11, 2025Peer-reviewedBiochemistry✦ In-depth digest