Ambuj Kumar

This study investigates HES3's role in development and fusion-positive rhabdomyosarcoma using zebrafish models and finds HES3 regulates neural programs and interacts with PAX3::FOXO1 to influence tumor biology.

This study identifies the SPP1-CD44 axis as an immunosuppressive pathway in pediatric high-grade glioma and develops an antibody to disrupt it using single-cell and structural bioinformatics.

MyeloDB is a multi-omics database for multiple myeloma that integrates gene expression, methylation, CRISPR screens, and drug sensitivity data to identify novel drug targets.

AMLdb is a multi-omics platform for AML research that identifies potential therapeutic targets, including five genes, with ENO1 as a novel candidate.