Author

Jian Li

Joslin Diabetes CenterORCID 0000-0003-3725-1383Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jian Li7 papers · Children's Hospital of Philadelphia

Biology Disciplines

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Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Kevin BodeiD· 2 shared Siying WeiiD· 2 shared Yi PengiD· 2 shared Alexander Lee-Papastavros· 1 shared Andy Ma· 1 shared Brooke Sullivan· 1 shared Isabella Gruber· 1 shared Jennifer Hollister‐LockiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Kevin BodeORCID

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2 papers

Recent·Most cited

ImmunologyFrontiers in ImmunologyPeer-reviewedJun 4, 2024

Beta Cells Deficient for Renalase Counteract Autoimmunity by Shaping Natural Killer Cell Activity

Kevin Bode, Siying Wei, Isabella Gruber…·Yi Peng

This study shows that beta cells lacking Renalase reduce autoimmunity by altering Natural Killer cell activity and enhancing anti-inflammatory responses.

8 citations

mouseproteomics

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GeneticsbioRxivPreprintMay 13, 2024

Loss-of-function of ALDH3B2 transdifferentiates human pancreatic duct cells into beta-like cells

Jian Li, Kevin Bode, Yu‐Chi Lee…·Yi Peng

This study shows that knocking out ALDH3B2 in human pancreatic duct cells converts them into beta-like cells that function and reduce blood glucose in mice.

DOI 10.1101/2024.05.13.593941

humanCRISPR screen

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