Misha Gupta

This study examines how epistasis and pleiotropy interact in complex traits using generic models and experimental data from yeast, showing that specific mutation patterns emerge under certain conditions.

The paper uses a broad range of yeast genotypes to assess epistasis in complex traits, finding limited contributions of epistasis to phenotypic variance.

This study compares adaptive routes in two yeast species after 10,000 generations, finding parallel but distinct molecular mechanisms of adaptation.

This study compares the fitness and robustness of two yeast strains under fluctuating and constant environments, finding that the lab strain improved fitness but not robustness, while the industrial strain became more robust.