Karl O. Persson

Impact of fluctuating environments on the fitness and robustness of evolving laboratory and industrial Saccharomyces cerevisiae strains

This study compares the fitness and robustness of two yeast strains under fluctuating and constant environments, finding that the lab strain improved fitness but not robustness, while the industrial strain became more robust.

Reproductive isolation due to divergent ecological selection is accompanied by vast genomic instability in experimentally evolved yeast populations

This study shows that divergent ecological selection in yeast leads to reproductive isolation and genomic instability through hybrid breakdown and structural variants.

Aborting meiosis overcomes hybrid sterility

Aborting meiosis followed by return-to-growth promotes genome-wide recombination in sterile yeast hybrids, enabling adaptation and genetic mapping.

Intragenic repeat expansions control yeast chronological aging

The paper identifies intragenic repeat expansions in yeast that influence chronological aging by altering cellular metabolism and environmental interaction.

Patterns of selection reveal shared molecular targets over short and long evolutionary timescales

The paper investigates how standing and de novo genetic variants contribute to drug adaptation in yeast, finding they act on shared molecular targets but via different mechanisms.

Contrasting genome dynamics between domesticated and wild yeasts

This study compares structural genome dynamics between domesticated and wild yeasts using long-read sequencing, revealing differences in rearrangement rates and types.