Nico Marx

The paper investigates altered ATP synthase dynamics in senescent hiPS-cardiomyocytes, linking structural changes in mitochondria to reduced enzyme activity and impaired cardiac function.

This study shows that reduced oxidative phosphorylation is not required for pro-inflammatory macrophage activation, challenging the conventional model of mitochondrial reprogramming.

This paper identifies that Mdivi-1 inhibits mitochondrial complex I, disrupts supercomplex assembly, and impairs neuronal activity by affecting ATP production and calcium homeostasis.