Guiscard Seebohm

This study compares the functional expression of two potassium channels, Kesv 1 and Kesv 2, identifying sequence differences that affect ion conductance and drug sensitivity.

The paper investigates altered ATP synthase dynamics in senescent hiPS-cardiomyocytes, linking structural changes in mitochondria to reduced enzyme activity and impaired cardiac function.

This study identifies TMPRSS6 cleavage of KCNE1 as a mechanism causing arrhythmias in iron overload disease using human iPSC-derived cardiomyocytes and computational models.

This paper identifies that Mdivi-1 inhibits mitochondrial complex I, disrupts supercomplex assembly, and impairs neuronal activity by affecting ATP production and calcium homeostasis.

Locityper improves variant calling for complex polymorphic genes using short and long-read sequencing, accurately genotyping 194 out of 256 challenging loci.

This paper shows that N-terminal tagging of Exo70 disrupts its assembly with the exocyst complex and alters its spatiotemporal behavior at the plasma membrane.

The paper identifies kcnk5b as a key regulator of allometric growth in zebrafish fins by integrating calcineurin signaling.