Sini Junttila

This study shows that disrupting the CIP2A gene reduces T cell-driven inflammation in experimental autoimmune encephalomyelitis.

Coralysis improves integration of imbalanced cell types and states in single-cell data by multi-level integration, outperforming existing methods in such scenarios.

The paper identifies unconjugated bilirubin as a protective metabolite against malaria by inhibiting parasite proliferation and hemozoin formation.

Totem is an R package that automates tree-shaped trajectory inference from single-cell data by generating and evaluating multiple clustering results.

This study benchmarks 18 methods for detecting differential states in multi-subject scRNA-seq data, finding that pseudo-bulk and mixed models outperform naive single-cell approaches by reducing false positives.

scShaper is a fast and accurate linear trajectory inference method for single-cell RNA-seq data, outperforming existing methods in accuracy and generalizability.

ILoReg improves cell population identification in single-cell RNA-seq by using probabilistic feature extraction before clustering.