Author

Y Chen

University of OxfordORCID 0000-0003-3758-0638Unclaimed ORCID profile · follow to get notified of new preprints

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Y Chen6 papers · Mayo Clinic

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Graham Stuart OggiD· 2 shared Adam P. CribbsiD· 1 shared Adam P. CroftiD· 1 shared Adam P. UldrichiD· 1 shared Adam ShahineiD· 1 shared Andrew D. FileriD· 1 shared Anna Adams· 1 shared Ariane HammitzschiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Graham Stuart OggORCID

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2 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedDec 31, 2025

Sideways lipid presentation by the antigen-presenting molecule CD1c

Thinh-Phat Cao, Guan‐Ru Liao, Tan‐Yun Cheng…·Jamie Rossjohn

This study identifies a mechanism by which CD1c presents two lipids simultaneously, with bulky headgroups oriented sideways, enabling autoreactive TCR recognition.

1 citation

humanproteomics

𝕏 PostBluesky

ImmunologyAnnals of the Rheumatic DiseasesPeer-reviewedMay 23, 2025

CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovium tissue

Feng Liu, Hui Shi, Jason D. Turner…·Liye Chen

This study identifies CD4+ tissue-resident memory Th17 (TRM17) cells as the main source of IL-17A in SpA synovium, showing their role in disease pathology and potential as therapeutic targets.

23 citationstop 1%

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