Author

Adam P. Uldrich

The University of MelbourneORCID 0000-0002-6350-5976Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Dale Ian GodfreyiD· 2 shared Jamie RossjohniD· 2 shared Nicholas A. GherardiniD· 2 shared Adam ShahineiD· 1 shared Alexandra Jane CorbettiD· 1 shared Alexis Perez‐GonzaleziD· 1 shared Ashlyn S. KerriD· 1 shared Ashraful HaqueiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

Dale Ian GodfreyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Specific targeting of MR1-antigen complexes using nanobodies

Hisham S. Hussain, Samuel J. Redmond, Wael Awad, Calvin Xu, Caroline Soliman, Huimeng Wang, Yuyang Zhang, Lisa Ciacchi, Alexis Perez‐Gonzalez, Jeffrey Y. W. Mak, David P. Fairlie, James McCluskey, Alexandra Jane Corbett, Adam P. Uldrich, Jamie Rossjohn, , Nicholas A. Gherardin

The paper develops a nanobody targeting MR1-5-OP-RU complexes and demonstrates its ability to modulate MAIT cell responses and act as a bispecific engager.

Science Immunology · Sep 25, 2026Peer-reviewedImmunology

Temporally overlapping mechanisms diversify clonal B cell responses in vivo.

Oliver P. Skinner, Saba Asad, Marcela L. Moreira, Hyun Jae Lee, Cameron G. Williams, Zheng Ruan, Jorene Lim, Ashlyn S. Kerr, Shihan Li, Chen Zhu, Wang Jin, Thiago Maass Steiner, Takahiro Asatsuma, Brooke J. Wanrooy, Zihan Liu, , Ashraful Haque

Single-cell RNA and BCR sequencing of infected mouse spleens shows class switching overlaps clonal expansion, GC-seeding clones also form plasmablasts, and SHM proceeds at constant rate.

Nature Immunology · Jun 15, 2026Peer-reviewedImmunology✦ In-depth digest

Sideways lipid presentation by the antigen-presenting molecule CD1c

Thinh-Phat Cao, Guan‐Ru Liao, Tan‐Yun Cheng, Yanqiong Chen, Laura Ciacchi, Thomas S. Fulford, Rachel Farquhar, Jade Kollmorgen, Jacob A. Mayfield, Adam P. Uldrich, Emily Zhi Qing Ng, Graham Stuart Ogg, Dale Ian Godfrey, Nicholas A. Gherardin, Y Chen, , Jamie Rossjohn

This study identifies a mechanism by which CD1c presents two lipids simultaneously, with bulky headgroups oriented sideways, enabling autoreactive TCR recognition.

Nature Communications · Dec 31, 2025Peer-reviewedImmunology