Satoshi Sawai

This study identifies surface tension and stalk elongation as key mechanical drivers of fruiting body formation in Dictyostelium discoideum using a hydrodynamic model and experimental measurements.

This study shows phospholipase D (PLD) reduces lipid and protein diffusion in membranes by producing phosphatidic acid, which affects phosphoinositide signaling and membrane protrusion.

This study shows Dictyostelium discoideum transitions to a mesenchymal-like migration mode on highly adhesive substrates, characterized by specific morphological and mechanical features.

This paper develops a nanobody-based degron system for targeted protein knockdown in Dictyostelium discoideum, demonstrating cell type-specific degradation and validating its efficacy.

The paper shows antiparallel cell circulation arises from self-aligned polarity-dependent tension gradients in confluent tissues.

This study investigates how neutrophil-like HL-60 cells respond to traveling waves of chemoattractants, finding that cell movement depends on wave speed and involves different signaling pathways at the front and back of the wave.

This study demonstrates the feasibility of 4- and 5-color fluorescence imaging in Dictyostelium discoideum using new fluorescent proteins and labels.