Hidenori Hashimura

This study identifies surface tension and stalk elongation as key mechanical drivers of fruiting body formation in Dictyostelium discoideum using a hydrodynamic model and experimental measurements.

This study shows phospholipase D (PLD) reduces lipid and protein diffusion in membranes by producing phosphatidic acid, which affects phosphoinositide signaling and membrane protrusion.

This study shows Dictyostelium discoideum transitions to a mesenchymal-like migration mode on highly adhesive substrates, characterized by specific morphological and mechanical features.

This paper develops a nanobody-based degron system for targeted protein knockdown in Dictyostelium discoideum, demonstrating cell type-specific degradation and validating its efficacy.

The paper shows antiparallel cell circulation arises from self-aligned polarity-dependent tension gradients in confluent tissues.

This study demonstrates the feasibility of 4- and 5-color fluorescence imaging in Dictyostelium discoideum using new fluorescent proteins and labels.

The paper uses live-imaging to show calcium signaling via ER and extracellular pathways mediates mechanosensing during multicellular development in Dictyostelium.