José Reina

This paper shows EWS::FLI1 can activate GGAASat sequences into enhancers in yeast, suggesting this function is ancient, while broader transcriptome changes require animal-specific factors.

The paper identifies Cabeza as a necessary cofactor for ETV4-mediated activation of GGAA microsatellite enhancers in Drosophila, showing distinct mechanisms from EWS::FLI1.

The paper identifies a novel form of gene expression instability, called Illuminati, in Drosophila neural stem cells, showing it is environmentally influenced and can persist through multiple cell cycles.