Cayetano González

Ancient and Animal-Specific Regulatory Modes of EWS::FLI1 Revealed by a Minimal Yeast Model.

This paper shows EWS::FLI1 can activate GGAASat sequences into enhancers in yeast, suggesting this function is ancient, while broader transcriptome changes require animal-specific factors.

The Drosophila FET orthologue Cabeza is an essential cofactor for ETV4-mediated activation of GGAA microsatellite neoenhancers

The paper identifies Cabeza as a necessary cofactor for ETV4-mediated activation of GGAA microsatellite enhancers in Drosophila, showing distinct mechanisms from EWS::FLI1.

Illuminati, a novel form of gene expression plasticity in Drosophila neural stem cells

The paper identifies a novel form of gene expression instability, called Illuminati, in Drosophila neural stem cells, showing it is environmentally influenced and can persist through multiple cell cycles.

Tumour Suppressor Parafibromin/Hyrax Governs Cell Polarity and Centrosome Assembly in Neural Stem Cells

This study shows that Parafibromin/Hyrax regulates cell polarity and centrosome assembly in neural stem cells, preventing overgrowth and tumour formation.

Structures of the germline-specific Deadhead and Thioredoxin T proteins from Drosophila melanogaster reveal unique features among Thioredoxins

The paper presents the first structures of Drosophila germline-specific Thioredoxins, Dhd and TrxT, revealing unique structural features and their potential roles in redox regulation and chromatin remodeling.