Author

Arif Dönmez

Leibniz Institute of Environmental MedicineORCID 0000-0003-3828-7724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:database / resource· 1

Frequent Co-Authors

Katharina KochiD· 3 shared Ellen FritscheiD· 2 shared Andrea Borchardt· 1 shared Andreas S. ReichertiD· 1 shared Arun Kumar KondadiiD· 1 shared Axel Mosig AiD· 1 shared Gabriele Brockerhoff· 1 shared Gerhard FritziD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBioinformatics

Katharina KochORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 19, 2026

ToxCastLite: A portable semantic evidence graph linking in vitro bioactivity, in vivo toxicity, and exposure-use context

Arif Dönmez, Oleksiy Nosov, Kristina Heck…·Katharina Koch

ToxCastLite provides a portable semantic evidence system linking in vitro bioactivity, in vivo toxicity, and exposure context for toxicology research.

DOI 10.64898/2026.05.16.724895

statistical modeldatabase / resource

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Cell BiologybioRxivPreprintApr 18, 2025

Preconditioning of human iPSCs with doxorubicin causes genome-wide transcriptional reprogramming in iPSC-derived cardiomyocytes linked to mitochondrial dysfunction and impaired cardiac regeneration

Michelle Westerhoff, Nahal Brocke‐Ahmadinejad, Yulia Schaumkessel…·Andreas S. Reichert

This study shows that low-dose doxorubicin treatment of human iPSCs causes mitochondrial dysfunction and transcriptional changes that impair cardiac regeneration in derived cardiomyocytes.

1 citation

humanbulk RNA-seq

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NeuroscienceCellsPeer-reviewedApr 27, 2023

Molecular and functional characterization of different BrainSphere models for use in neurotoxicity testing on microelectrode arrays

Julia Hartmann, Noah Henschel, Kristina Bartmann…·Ellen Fritsche

The paper characterizes different BrainSphere models for neurotoxicity testing using microelectrode arrays, finding that media choice affects differentiation patterns and functional activity.

29 citations

humanbulk RNA-seq

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