Andreas S. Reichert

This study shows Ubp3 dynamically regulates mitochondrial ubiquitination during mitophagy, revealing its role in ubiquitin storage and release as a stress response mechanism.

This study shows that the catalytic activity of Ubp3, a yeast deubiquitinase, is independent of its interaction partner Bre5, challenging the current model of Bre5-dependent activation.

The paper identifies the proximity interactome of the MICOS complex using APEX2 fusion proteins, revealing a network of proteins involved in mitochondrial biogenesis and function.

This study compares the response of murine embryonic stem cells and their endothelial progeny to doxorubicin and DNA repair inhibitors, finding differential susceptibility and functional impairments in differentiated cells.

This study shows that low-dose doxorubicin treatment of human iPSCs causes mitochondrial dysfunction and transcriptional changes that impair cardiac regeneration in derived cardiomyocytes.

This study identifies NECAB2's role in an endosomal pathway for mitochondrial stress response and repair in striatal synapses, linking its loss to synaptic loss and behavioral deficits.