Author

Michelle Westerhoff

Düsseldorf University HospitalORCID 0009-0000-1569-8446Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andreas S. ReichertiD· 2 shared Gerhard FritziD· 2 shared Andrea Borchardt· 1 shared Arif DönmeziD· 1 shared Arun Kumar KondadiiD· 1 shared Julia TiggesiD· 1 shared Karl KöhreriD· 1 shared Katharina KochiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPharmacology & Toxicology

Andreas S. ReichertORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintMay 15, 2025

Differential responses of murine embryonic stem cells (mESC) and their endothelial progeny to doxorubicin and pharmacological inhibitors of DNA repair and DNA damage response

Sina Federmann, Michelle Westerhoff, Andreas S. Reichert, Gerhard Fritz

This study compares the response of murine embryonic stem cells and their endothelial progeny to doxorubicin and DNA repair inhibitors, finding differential susceptibility and functional impairments in differentiated cells.

1 citation

mouseproteomics

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Cell BiologybioRxivPreprintApr 18, 2025

Preconditioning of human iPSCs with doxorubicin causes genome-wide transcriptional reprogramming in iPSC-derived cardiomyocytes linked to mitochondrial dysfunction and impaired cardiac regeneration

Michelle Westerhoff, Nahal Brocke‐Ahmadinejad, Yulia Schaumkessel…·Andreas S. Reichert

This study shows that low-dose doxorubicin treatment of human iPSCs causes mitochondrial dysfunction and transcriptional changes that impair cardiac regeneration in derived cardiomyocytes.

1 citation

humanbulk RNA-seq

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