Author

Harini Srinivasan

Broad InstituteORCID 0000-0003-3834-424XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Christopher L. JacobsiD· 2 shared Anne M.J. VerstegeniD· 1 shared Anton GulkoiD· 1 shared Antonino ZitoiD· 1 shared Anwar TandariD· 1 shared Aykut Göktürk ÜneriD· 1 shared Bradford B. LowelliD· 1 shared Charles Y. LuiiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersNeuroscience

Christopher L. JacobsORCID

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3 papers

Recent·Most cited

PhysiologybioRxivPreprintFeb 11, 2025

Peroxisome proliferator-activated receptor gamma (PPARG)-mediated myocardial salvage in acute myocardial infarction managed with left ventricular unloading and coronary reperfusion

Joseph R. Visker, Eleni Tseliou, Christos P. Kyriakopoulos…·Stavros Drakos

This study investigates the mechanisms of myocardial salvage in acute myocardial infarction using left ventricular unloading and reperfusion, identifying PPARG as a key cardioprotective gene and suggesting rosiglitazone as a potential adjuvant therapy.

1 citation

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceNature CommunicationsPeer-reviewedMay 31, 2024

Integrated genomic analysis of AgRP neurons reveals that IRF3 regulates leptin's hunger-suppressing effects

Frankie D. Heyward, Nan Liu, Christopher L. Jacobs…·Evan D. Rosen

The paper identifies IRF3 as a key transcriptional regulator of leptin's hunger-suppressing effects in AgRP neurons through integrated genomic analysis.

13 citations

mousescRNA-seq

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NeuroscienceNature CommunicationsPeer-reviewedMar 4, 2024

A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution

Stefano Nardone, Roberto De Luca, Antonino Zito…·Bradford B. Lowell

This study creates a spatially-resolved transcriptional atlas of the murine dorsal pons using snRNA-seq and MERFISH, identifying 120 neuronal subtypes and their spatial distribution.

60 citationstop 1%

mousesnRNA-seq

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