BioengineeringJournal of the American Chemical SocietyPeer-reviewed
Bottlebrush polymers with sequence-controlled backbones for enhanced oligonucleotide delivery
Yun Wei, Peiru Chen, Mengqi Ren…·Ke Zhang
This paper develops sequence-controlled PEG bottlebrush polymers for enhanced oligonucleotide delivery, showing improved cellular uptake and in vivo antisense activity through optimized chemical modifications.