Deng Li

This study compares enhanced sampling methods for RNA conformational sampling, finding T-REMD provides the most accurate ensembles and improves virtual screening.

This study uses molecular dynamics to analyze conformational changes in surfactant protein B at the alveolar air/liquid interface, revealing stability of the closed conformation and hydrophobic-driven changes in the open conformation.

This study identifies a biomechanical mechanism involving mesenchymal forces and SHH signaling that drives epithelial tube splitting during tracheal-esophageal separation in embryos.

This paper develops sequence-controlled PEG bottlebrush polymers for enhanced oligonucleotide delivery, showing improved cellular uptake and in vivo antisense activity through optimized chemical modifications.