Cancer BiologyScience AdvancesPeer-reviewed
Metabolic shift to serine pathway induced by lipids confers oncogenic properties in non-transformed breast cells
Mariana Bustamante Eduardo, Gannon Cottone, Curtis W. McCloskey…·Susan E. Clare
The paper shows that lipid metabolism, specifically through OA, shifts metabolic pathways in breast cells, increasing SAM and 2-HG, which contribute to oncogenic properties and epigenetic changes.
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