Liu Yang

This study introduces fungal-DBiT, a spatial transcriptomic platform that maps host and fungal RNAs in tissue sections, revealing spatial heterogeneity in fungal localization and host responses during infection and under physiological conditions.

This study identifies ECM-dominant cardiovascular diseases as driven by coordinated CDKN1A and CDKN2A senescence programs in fibroblasts and shows senolytic treatments improve cardiac function.

This study identifies PGRP-LA as a regulator of peritrophic matrix integrity in tsetse flies, influencing trypanosome infection outcomes by modulating gut barrier function rather than canonical immune signaling.

The paper co-sequences microRNAs and mRNAs in single cells to show miRNA variability contributes to non-genetic cell-to-cell heterogeneity and identifies new regulatory relationships.