Author

Laxmikanta Khamari

University of MichiganORCID 0000-0003-3922-7862Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Jingxuan Tang· 2 shared Nils G. WalteriD· 2 shared Stephanie L. MooniD· 2 shared Benjamin J. T. Dodd· 1 shared Guoming GaoiD· 1 shared Liuhan DaiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Jingxuan Tang

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiophysicsbioRxivPreprintMay 8, 2026

ASPL-driven subunit exchange remodels VCP/p97 hexamers and is impaired by a multisystem proteinopathy mutation

Jingxuan Tang, Laxmikanta Khamari, Benjamin J. T. Dodd…·Nils G. Walter

The paper quantifies VCP hexamer assembly and subunit exchange dynamics, showing that the R155H mutation impairs ASPL-mediated exchange, potentially stabilizing mutant VCP in assemblies.

DOI 10.64898/2026.05.07.723621

humanexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintMay 5, 2026

Npl4 decodes polyubiquitin length and gates D1-D2 coupling in human VCP/p97

Laxmikanta Khamari, Jingxuan Tang, Stephanie L. Moon, Nils G. Walter

This study investigates how Npl4 decodes polyubiquitin chain length and regulates D1-D2 coupling in human VCP/p97 using smUbiRAD, revealing chain-length thresholds and disease-linked mutations.

DOI 10.64898/2026.05.01.722286

humanproteomics

𝕏 PostBluesky