Kevin C. Gonzalez

This study shows that neuronal activity drives local CaMKII synthesis and localization via autophosphorylation-dependent pathways, leading to spatially and functionally distinct CaMKII populations.

The paper uses two-photon imaging and electrophysiological recordings to study dendritic membrane potential dynamics in mouse hippocampal pyramidal cells during behavior, revealing spatial and temporal patterns of electrical signaling.

The paper experimentally tests a model of synaptic plasticity in awake mice, showing asymmetric potentiation and depression of synaptic inputs around plateau spikes and compartment-specific differences in plasticity.

This study identifies cis-regulatory elements that regulate horizontal cell development by analyzing enhancer activity and transcription factor interactions.

This study uses CRISPR/Cas9 to disrupt OTX2 in retinal progenitors, revealing its role in suppressing alternative cell fates and maintaining proliferative potential.