Author

Xiaochun Zhang

Tsinghua UniversityORCID 0000-0003-3963-8864Unclaimed ORCID profile · follow to get notified of new preprints

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Xiaochun Zhang6 papers · Washington University in St. Louis

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Bailong XiaoiD· 1 shared Boxue TianiD· 1 shared Chao LiniD· 1 shared Chenxi WangiD· 1 shared Jingyi YuaniD· 1 shared Sijia LiuiD· 1 shared Xueming LiiD· 1 shared Xuzhong YangiD· 1 shared

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2025-2025 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Bailong XiaoORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintNov 17, 2025

A disease mutation reveals a non-swapped pore and rewired gating cycle of the mechanically activated PIEZO1 channel

Chenxi Wang, Ziying Zhang, Xuzhong Yang…·Bailong Xiao

This paper investigates the structural and functional changes in the PIEZO1-R2482H mutant, revealing a non-swapped pore and altered gating cycle that explain its heightened mechanosensitivity and slowed inactivation.

DOI 10.1101/2025.11.17.688653

humanstructural biology

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