Author

Chenxi Wang

Center for Life SciencesORCID 0000-0002-9547-1547Unclaimed ORCID profile · follow to get notified of new preprints

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Chenxi Wang2 papers · University of Science and Technology of China

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Bailong XiaoiD· 2 shared Boxue TianiD· 1 shared Chao LiniD· 1 shared Jingyi YuaniD· 1 shared Lu Yan· 1 shared Meiqi LiiD· 1 shared Ning GaoiD· 1 shared Peng XiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Bailong XiaoORCID

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2 papers

Recent·Most cited

A disease mutation reveals a non-swapped pore and rewired gating cycle of the mechanically activated PIEZO1 channel

Chenxi Wang, Ziying Zhang, Xuzhong Yang, Sijia Liu, Jingyi Yuan, Chao Lin, Xiaochun Zhang, Boxue Tian, Xueming Li, Bailong Xiao

This paper investigates the structural and functional changes in the PIEZO1-R2482H mutant, revealing a non-swapped pore and altered gating cycle that explain its heightened mechanosensitivity and slowed inactivation.

bioRxiv · Nov 17, 2025 · PreprintBiophysics

Structural Role of Stomatin in Organizing Functional Membrane Microdomains

Lu Yan, Xinyue Zhou, Meiqi Li, Chenxi Wang, Bailong Xiao, Peng Xi, Peng Zou, Ning Gao

This study determines the cryo-EM structure of stomatin, revealing its role in organizing functional membrane microdomains and identifying associated proteins involved in cell migration and vesicle trafficking.

bioRxiv · Aug 30, 2025 · PreprintBiophysics