Author

Chao Lin

Tsinghua UniversityORCID 0000-0001-8949-8244Unclaimed ORCID profile · follow to get notified of new preprints

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Chao Lin1 paper · Howard Hughes Medical Institute

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Xueming LiiD· 2 shared Bailong XiaoiD· 1 shared Boxue TianiD· 1 shared Chenxi WangiD· 1 shared Haitao LiiD· 1 shared Jingyi YuaniD· 1 shared Qianwen SuniD· 1 shared Qin LiiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Xueming LiORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintNov 17, 2025

A disease mutation reveals a non-swapped pore and rewired gating cycle of the mechanically activated PIEZO1 channel

Chenxi Wang, Ziying Zhang, Xuzhong Yang…·Bailong Xiao

This paper investigates the structural and functional changes in the PIEZO1-R2482H mutant, revealing a non-swapped pore and altered gating cycle that explain its heightened mechanosensitivity and slowed inactivation.

DOI 10.1101/2025.11.17.688653

humanstructural biology

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Molecular BiologyJournal of genetics and genomics/Journal of Genetics and GenomicsPeer-reviewedMay 10, 2022

Cryo-EM Structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids

Qin Li, Chao Lin, Zhipu Luo…·Qianwen Sun

This study determines the cryo-EM structure of the S9.6 antibody Fab bound to RNA:DNA hybrids, revealing its recognition mechanism and binding specificity.

9 citations

protein structureexperimental assay

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