Author

Vijay Bhoopalan

Australian National UniversityORCID 0000-0003-3972-9256Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Nadine HeiniD· 2 shared Rita FerreiraiD· 2 shared Ross D. HannaniD· 2 shared Adrià ClosaiD· 1 shared Amandeep KauriD· 1 shared Amee J. GeorgeiD· 1 shared Cathryn M. Gould· 1 shared Dani Tutuka· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Nadine HeinORCID

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2 papers

Recent·Most cited

Cancer BiologyLeukemiaPeer-reviewedOct 8, 2026

Novel RNA Polymerase I and Cyclin Dependent Kinase combination therapy for the treatment of aggressive Acute Myeloid Leukemia.

Nadine Hein, Perlita Poh, Jason A. Powell…·Rita Ferreira

This paper identifies a synergistic combination of RNA Polymerase I inhibitor CX-5461 and CDK inhibitor Dinaciclib that enhances therapeutic efficacy in AML by inducing nucleolar stress and cell cycle arrest.

DOI 10.1038/s41375-026-03148-1

humanmouse

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Cell BiologybioRxivPreprintJun 15, 2025

Treatment with the ribosome biogenesis inhibitor CX-5461 increases platelet count in humans and enhances murine megakaryopoiesis

Vijay Bhoopalan, Amandeep Kaur, James I. Hearn…·Elizabeth E. Gardiner

The paper shows that CX-5461, a ribosome biogenesis inhibitor, increases platelet counts in humans and enhances megakaryopoiesis in mice without affecting platelet function or inflammatory cytokines.

DOI 10.1101/2025.06.15.659730

humanmouse

𝕏 PostBluesky