Jérémy Chantrel

This study shows that senescence during postpartum mammary gland involution supports tissue remodeling but also promotes tumorigenesis by enhancing tumor-initiating cell plasticity.

This study shows genetic and chemical partial reprogramming targets senescent cells to reduce aging-related inflammation and improve mitochondrial function in aged mice without restoring proliferation.

The paper identifies senescent fibro-adipogenic progenitors (FAPs) as pro-regenerative in muscle regeneration using single-cell RNA sequencing in mice.