Author

Young-Hoon Park

University of PennsylvaniaORCID 0000-0003-4016-8652Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:non-human primate· 1

Frequent Co-Authors

Beatrice H. HahniD· 3 shared George M. ShawiD· 3 shared Kevin J. WieheiD· 3 shared Khaled AmerehiD· 3 shared Raiees AndrabiiD· 3 shared Rumi HabibiD· 3 shared Xuduo LiiD· 3 shared Agnes A. Walsh· 2 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Beatrice H. HahnORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 6, 2025

Consistent Induction of Broadly Neutralizing HIV Antibodies by a Novel Two-Step Mechanism Informs Immunogen Design

Ashwin N. Skelly, Harry B. Gristick, Hui Li…·George M. Shaw

This study shows a novel two-step mechanism for inducing broadly neutralizing HIV antibodies in macaques using a modified SHIV, informing vaccine design.

3 citations

non-human primateexperimental assay

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ImmunologybioRxivPreprintJun 12, 2025

Rapid acquisition of HIV-1 neutralization breadth in a rhesus V2 apex germline antibody mouse model after a single bolus immunization

Amrit Raj Ghosh, Rumi Habib, Nitesh Mishra…·Facundo D. Batista

This study shows that a single immunization with a germline-targeting trimer can induce broad HIV-1 neutralizing antibodies in a rhesus macaque bnAb mouse model.

2 citations

ratspatial transcriptomics

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ImmunologybioRxivPreprintMay 3, 2025

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Rumi Habib, Ryan S. Roark, Hui Li…·George M. Shaw

The paper identifies B cell priming as the main obstacle to developing HIV-1 V2 apex broadly neutralizing antibodies in SHIV-infected macaques.

8 citations

ratproteomics

𝕏 PostBluesky