Sophia Mason

This paper develops wzi-Seq, a method to detect and quantify Klebsiella strains in gut samples, and finds that mono-colonization is associated with increased infection risk.

This study tracks Klebsiella pneumoniae dissemination from the lung using barcoding, revealing two distinct patterns of bacterial spread and their associated host and bacterial factors.

The paper identifies 18 conserved fitness genes in Enterobacterales species that contribute to bacteremia pathogenesis by testing mutants in a mouse model and finding attenuation in multiple organs.

The paper integrates Tn-Seq fitness data with functional data to identify seven common fitness mechanisms across five Enterobacterales species, validating one gene's role in bacteremia and antibiotic resistance.