Jean‐René Martin

The paper shows that specific snoRNAs pseudouridylate rRNA, affecting ribosome function, lipid metabolism, and neurodegeneration in Drosophila.

The paper identifies three snoRNAs in Drosophila that regulate lifespan and neuroprotection through metabolic pathways in the gut and brain.

This study shows that knocking down snoRNA-jouvence in human glioblastoma cells reduces proliferation and induces apoptosis, suggesting it as a potential therapeutic target.

The paper shows that ninaD, a gene upregulated in gut cells, regulates cholesterol homeostasis and protects against neurodegeneration by a gut-brain axis mechanism.

This study characterizes a new human H/ACA snoRNA, jouvence, showing it promotes cell proliferation and dedifferentiation while its knockdown reduces proliferation and ribosome biogenesis.

This paper identifies a new Drosophila snoRNA, jouvence, that extends lifespan when overexpressed and reduces it when lost, suggesting a role in transcriptional control and evolutionary conservation.

The paper identifies a lineage-related reciprocal inhibition circuit in Drosophila that mediates sensory-motor action selection through competitive inhibition.