Author

Zuolian Shen

University of UtahORCID 0000-0003-4069-306XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Dean R TantiniD· 3 shared Mahesh B. ChandrasekharaniD· 3 shared Yifan WuiD· 3 shared Asit Kumar MannaiD· 2 shared Bradley Robert CairnsiD· 1 shared Chongil YiiD· 1 shared Erik P. HughesiD· 1 shared Hiroshi HandaiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMolecular Biology

Dean R TantinORCID

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3 papers

Recent·Most cited

Molecular BiologyJournal of Biological ChemistryPeer-reviewedOct 25, 2025

Jade1 and the HBO1 histone acetyltransferase complex are spatial-selective cofactors of the pluripotency transcription factor Oct4

Yifan Wu, Asit Kumar Manna, Li Li…·Dean R Tantin

The paper identifies Jade1 as a cofactor of Oct4 that selectively interacts with specific DNA configurations to enhance histone acetylation and transcriptional regulation.

2 citations

mouseChIP-seq

𝕏 PostBluesky

Molecular BiologybioRxivFeb 21, 2023

Oct4 redox sensitivity potentiates reprogramming and differentiation

Zuolian Shen, Yifan Wu, Asit Kumar Manna…·Dean R Tantin

This study identifies a redox-sensitive cysteine residue in Oct4 that regulates reprogramming and differentiation by affecting DNA binding and ubiquitylation.

5 citations

mouseexperimental assay

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Developmental BiologybioRxivPreprintDec 1, 2020

Oct1 cooperates with Smad transcription factors to promote mesodermal lineage specification

Jelena Perovanović, Yifan Wu, Hosiana Abewe…·Dean R Tantin

This study shows that Oct1 works with Smad factors to activate mesodermal genes during differentiation, improving understanding of lineage specification.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky