Carlos A. Pinzón-Arteaga

This study benchmarks and optimizes Perturb-seq in human pluripotent stem cells, identifying shared regulatory networks during cardiomyocyte differentiation.

This study identifies factors required for establishing and maintaining mammalian heterochromatin, showing that DHX9 and H3K9me erasers influence its stability during differentiation.

This study shows that a mutation in FicD causes diabetes by disrupting BiP AMPylation and pancreatic endocrine homeostasis in mice.

This study identifies TASOR's role in maintaining developmental potential during the transition from naive to primed pluripotency by preventing L1 transposable element activation and subsequent cell death.

This paper develops an optimized protocol for large-scale production of human blastoids and identifies signaling pathways and endometrial stromal effects in blastocyst development.

The paper develops a method to generate bovine blastocyst-like structures (blastoids) from stem cells, which mimic blastocysts in morphology and transcriptomes.

This study uses a chemical cocktail to derive and culture bovine trophoblast stem cells, which retain developmental potency.