Author

Kartik Kulkarni

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

Nikhil V Munshi· 2 shared Abir MajumdariD· 1 shared Adam OsinskiiD· 1 shared Ann JohnsoniD· 1 shared B Li· 1 shared Brenden C. Park· 1 shared Brian HasselliD· 1 shared Cassie L. BehrendtiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersGenomics

Nikhil V Munshi

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Author profile →

3 papers

Recent·Most cited

Combinatorial transcription factor interactions drive modular gene regulatory networks

Jialei Duan, B Li, Kartik Kulkarni, Gabriela Orquera-Tornakian, Daryl Barth, L H Wang, Vrushali Pandit, Joel Liou, Nikhil V Munshi, Gary C. Hon

The paper uses single-cell overexpression screens to study how combinations of transcription factors drive gene regulatory networks and cell-type specific gene expression programs.

bioRxiv · May 21, 2026 · PreprintGenomics

Epithelial sensing of vitamin A shapes intestinal antimicrobial defense

Gabriella M. Quinn, Daniel C. Propheter, Kartik Kulkarni, Matthew Johnson, Goncalo Dias do Vale, Jeffrey G. McDonald, Ann Johnson, Brian Hassell, Cassie L. Behrendt, Nikhil V Munshi, Lora V. Hooper

This study shows dietary vitamin A enhances intestinal antimicrobial defenses by promoting REG3 lectin and defensin expression through retinoic acid receptor signaling.

bioRxiv · Mar 10, 2026 · PreprintImmunology

Bacterial ubiquitin ligase engineered for small molecule and protein target identification

James S. Ye, Abir Majumdar, Brenden C. Park, Miles H. Black, Ting‐Sung Hsieh, Adam Osinski, Kelly A. Servage, Kartik Kulkarni, Jacinth Naidoo, Neal M. Alto, Margaret M. Stratton, Dominique Alfandari, Joseph M. Ready, Krzysztof Pawłowski, Diana R. Tomchick, Vincent S. Tagliabracci

This paper introduces SidBait, a modular proximity ligation approach to identify small molecule and protein targets, validated with known interactions and applied to discover new targets like CaMKII and CapZ.

The EMBO Journal · Jan 3, 2026Peer-reviewedMolecular Biology