Mazène Hochane

This study introduces proxiloids, a scalable human-induced pluripotent stem cell differentiation method that models kidney proximal tubule toxicity more accurately than existing methods.

The paper captures two human axial stem cell states and identifies regulatory networks and mechanisms underlying their maintenance and differentiation.

The paper introduces SIGMA, a clusterability measure to identify meaningful subpopulations in single-cell transcriptomics data, leading to the discovery of previously overlooked phenotypes.

The paper shows that adding XEN cells to mouse gastruloids induces neuroepithelial tissue formation through reciprocal differentiation and WNT signaling inhibition.