Ava C. Carter

This study identifies BAF complex interaction with FOS in regulating ASD-associated gene programs through enhancer activation and shows how genetic variants disrupt this process.

The paper identifies human-specific activity-dependent genes regulated by FOS-bound enhancers, showing their role in human brain development evolution.

The paper uses human-chimpanzee tetraploid cells to identify cis-acting gene regulatory changes contributing to human neural specializations.

This study maps RNA translation dynamics in the human brain using ribosome profiling, identifying thousands of novel translation events and brain-specific microproteins linked to schizophrenia.

The paper investigates random monoallelic expression (RME) in F1 hybrid mouse cells before and after differentiation, revealing gene-specific, epigenetically regulated modes of allelic expression.

This study shows Spen binds to endogenous retroviral RNAs and recruits chromatin silencing machinery, linking RNA-mediated retrovirus silencing to X chromosome inactivation.

The paper studies chromosomal evolution in cancer cell lines, finding that cells lose sex chromosomes and gain autosomes, leading to a 2:3 X:A ratio that may enhance fitness.

Omni-ATAC improves ATAC-seq by reducing background noise and enabling analysis of frozen tissues, revealing disease-associated DNA element activities in human brain structures.