Michelle M. McCarthy

This paper introduces a computational model of a thalamocortical neuron that demonstrates how the awake alpha rhythm enables thalamic filtering of retinal signals and processing of non-sensory rhythms.

This paper uses a biophysical model of the basolateral amygdala to show that specific interneurons generate rhythms critical for fear learning and plasticity.

This study shows how ketamine's effects on NMDA receptor kinetics lead to oscillatory brain dynamics observed in EEG and local field potential recordings.

This paper constructs a biophysical thalamocortical model to simulate propofol-induced EEG changes, revealing two dynamic states linked to cortical synchronization and brainstem influence.

This study uses a biophysical model to show how deep brain stimulation (DBS) of the subthalamic nucleus can restore normal striatal rhythms in Parkinson's disease by modulating fast spiking interneurons and cortical noise.

This paper proposes a biophysical model of striatal microcircuits showing how dopamine modulates gamma and beta oscillations interleaved at delta/theta frequencies to enable periodic motor control.

The paper presents a corticostriatal model showing how biased competition can occur without input bias through physiological asymmetries in striatal neurons.

This study shows that activating striatal cholinergic receptors increases beta oscillations in the corticostriatal loop, with directional connectivity and subband-specific effects.