Don B. Arnold

The paper introduces Synapse-seq, a method to link transcriptomes to synaptic architecture by using protein-guided RNA barcoding, revealing new insights into neural connectivity and cell type-specific dendritic structures.

The paper identifies a cluster of negative valence neurons in the larval zebrafish pallium that respond to strongly noxious stimuli.

This study identifies a hippocampal-striatal circuit that regulates impulsive action in male rats, using chemogenetic and fiber photometry approaches.

The paper introduces ATLAS, an anterograde transsynaptic tracer based on an antibody-like protein, which enables non-toxic, synaptic, and activity-dependent circuit tracing in vivo and in dissociated cultures.

The paper introduces three genetically encoded tools to specifically ablate excitatory and inhibitory synapses using E3 ligase-dependent degradation mechanisms.

This paper uses a biophysical model of the basolateral amygdala to show that specific interneurons generate rhythms critical for fear learning and plasticity.

This study shows that distinct PFC subregions modulate VISp activity differently during behavior, with ACA enhancing visual encoding and ORB shaping movement and arousal-related responses.

The paper shows that suppressing molecular layer interneurons (MLIs) in mice enables climbing-fiber-mediated motor learning during the vestibulo-ocular reflex, even without performance errors.

The paper develops genetically-encoded reagents for cell-type specific synapse labeling and connectivity analysis in mouse brain tissue, revealing PV inputs as the dominant inhibitory source onto L2 pyramidal neurons.