Arach Goldar

This study develops a quantitative framework to infer PIC assembly paths in yeast using ChIP-seq data from Mediator mutants, revealing gene-specific and pathway-dependent variations.

This paper introduces a Bayesian model for DNA replication that infers origin timing and activation delays using RFD data, revealing 150 origins with significant delays in yeast.

The paper investigates DNA replication dynamics in Xenopus, identifying two replication modes with distinct fork speeds and origin firing rates, and shows Plk1's role in coordinating these processes.

This study uses functional Principal Component Analysis to analyze nucleosome positioning in yeast, revealing roles for RSC and Chd1 in gene body and upstream nucleosome organization.

The paper shows Mediator and RSC chromatin remodeling complex interact to maintain nucleosome-depleted regions at promoters in yeast.

The paper develops a quantitative modeling framework to analyze DNA repair kinetics in yeast, finding gene size correlates with repair rates.

The paper investigates the genome-wide distribution of Rad26 and Rad1-Rad10 in yeast, showing their association with Mediator and Pol II, and their distinct regulatory roles in transcription and DNA repair.