Inference on paths of yeast transcription pre-initiation complex assembly by model-based analysis of altered occupancy profiles
Elizaveta Novikova, Arach Goldar, Pierre Nicolas, Julie Soutourina
This study develops a quantitative framework to infer PIC assembly paths in yeast using ChIP-seq data from Mediator mutants, revealing gene-specific and pathway-dependent variations.
bioRxiv · Oct 2, 2026 · PreprintBioinformatics