Author

Jean‐Pierre Desvignes

InsermORCID 0000-0003-3142-1994Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

David SalgadoiD· 3 shared Stéphane ZaffraniD· 3 shared Michel PucéatiD· 2 shared Adèle FaucherreiD· 1 shared Alexander C. ZamboniD· 1 shared Alexis ThéroniD· 1 shared Amélie PinardiD· 1 shared André TerziciD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersDevelopmental Biology

David SalgadoORCID

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3 papers

Recent·Most cited

Developmental BiologyeLifePeer-reviewedAug 17, 2020

Hox-dependent coordination of cardiac progenitor cell patterning and differentiation

Sonia Stefanovic, Brigitte Laforest, Jean‐Pierre Desvignes…·Stéphane Zaffran

This study investigates the role of Hoxb1 in regulating cardiac progenitor cell patterning and differentiation, showing its negative regulation of posterior SHF differentiation and its impact on congenital heart defects.

58 citations

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivJan 23, 2019

Piezo1 is required for outflow tract and aortic valve development.

Adèle Faucherre, Hamid Moha ou Maati, Nathalie Nasr…·Chris Jopling

This study shows that PIEZO1 is essential for outflow tract and aortic valve development in zebrafish and identifies PIEZO1 variants linked to bicuspid aortic valve in humans.

87 citations

zebrafishexperimental assay

𝕏 PostBluesky

Developmental BiologybioRxivPreprintAug 22, 2018

A human cell model of cardiac pathophysiological valvulogenesis

Tui Néri, Emilye Hiriart, Patrick Piet Van Vliet…·Michel Pucéat

This paper develops a human pluripotent stem cell model to study valvulogenesis and disease, showing it can recapitulate valve development and disease traits like mitral valve prolapse.

DOI 10.1101/397422

humanbulk RNA-seq

𝕏 PostBluesky