Gaëlle Odelin

The paper analyzes clinical and genetic factors in patients with bicuspid aortic valve to identify predictors of valve dysfunction and genetic pathways involved in degeneration.

This study shows that PIEZO1 is essential for outflow tract and aortic valve development in zebrafish and identifies PIEZO1 variants linked to bicuspid aortic valve in humans.

The paper extends the random walk with restart algorithm to multiplex and heterogeneous biological networks to improve disease gene prediction.

This study shows that ectopic Hoxb1 expression in neural crest cells causes craniofacial and cardiac malformations, highlighting its role in development.